Glaucoma

Question 1

Background information for Ophthalmic Prostaglandin Analogs

Answer 1

Glaucoma is the uneven flow of aqueous humor (liquid in the eye) that leads to elevated pressure within the eye that damages the optic nerve leading to blindness

Question 2

Pharmacology of Ophthalmic Prostaglandin Analogs

Answer 2

Increases the outflow of aqueous humor, thus decreasing pressure within the eye. Prostaglandins are typically associated with inflammation but in the eye, they increase the outflow of aqueous humor

Question 3

Indications of Ophthalmic Prostaglandin Analogs

Answer 3

• Glaucoma

Question 4

Side effects of Ophthalmic Prostaglandins Analogs

Answer 4

• Eyelash growth
• Dry eye
• Blurred vision
• Discoloration of the iris
• Inflammation of the eye

Question 5

Important Note for Ophthalmic Prostaglandins Analogs

Answer 5

• Medication is in the form of eye drops
• Xalatan (Latanoprost) should be stored in the refrigerator until opened. Can be stored at room temp for up to 6 weeks
• Lumigan (Bimatoprost) and Travatan (Travoprost) can be stored at room temp

Question 6

What do Ophthalmic Prostaglandin Analogs end with?

Answer 6

“-oprost”

Question 7

Background information for Ophthalmic Beta-Blockers

Answer 7

Aqueous humor production also contributes to high intraocular pressure

Question 8

Pharmacology of Ophthalmic Beta-Blockers

Answer 8

Reduce the production of aqueous humor

Question 9

Indications of Ophthalmic Beta-Blockers

Answer 9

• Glaucoma

Question 10

Side effects of Ophthalmic Beta-Receptors

Answer 10

• Bradycardia
• Hypotension
• Asthma
• COPD

Question 11

Drug interactions of Ophthalmic Beta-Blockers

Answer 11

• May increase risk of hypotension and bradycardia when used with other drugs that can lower blood pressure and reduce heart rate