Insomnia

Question 1

Background information for Sedative-Hypnotics

Answer 1

The BNZ, benzodiazepine receptor can be activated by gamma-aminobutyric acid (GABA), the chief inhibitory neurotransmitter of the central nervous system. Activation of the BNZ1 receptor promotes sleep

Question 2

Pharmacology of Sedative-Hypnotics

Answer 2

Bind to the GABA-benzodiazepine receptor complex, enhancing the effect of GABA to promote sleep

Question 3

Indications of Sedative-Hypnotics

Answer 3

• Insomnia

Question 4

Side effects of Sedative-Hypnotics

Answer 4

• Drowsiness
• Somnolence
• Dependency

Question 5

Drug interactions of Sedative-Hypnotics

Answer 5

• Increased drowsiness when used with other drugs that suppress central nervous system activity

Question 6

Important note for Sedative-Hypnotics

Answer 6

All drugs in this class are C-IV