1
Q
Common in
A
older men
2
Q
Uric acid metabolism:
- lack of ____
- lack of ability to oxidise _____ to a soluble compound
A
- lack of uricase
- lack of ability to oxidise uric acid to a soluble compound
3
Q
Uricase is a normal byproduct of the breakdown of foods that contain _____
A
purines
4
Q
Attack of gout occurs when monosodium urate crystals ______ in the joint and initiate an ____________
A
precipitate;
an inflammatory response
5
Q
Clinical presentation
- monoarticular, usually first ______ joint
- precipitated by excessive exercise, certain meds or food, alcohol, or dieting — begins at ______
- ______ pain onset, ______, ______
- patient may be ______ in the early stages of gout
A
- monoarticular, usually first metatarsophalangeal joint
- precipitated by excessive exercise, certain meds or food, alcohol, or dieting — begins at night
- abrupt pain onset, redness, swelling
- patient may be asymptomatic in the early stages of gout
6
Q
Objective of treatment:
A
correction of hyperuricemia (inhibition of further precipitation of sodium urate, absorption of urate crystal deposits)
7
Q
Avoid what kind of food? Eg?
A
Purine-rich foods (they produce uric acid)
eg. seafood, red meat, organs, alcohol, aged cheese
8
Q
Medications and their uses
A
- NSAIDs
- Probenecid: eliminates uric acid
- Allopurinol: reduces production of uric acid
9
Q
Acute attack stage (nur management):
A
- bed rest with affected extremity elevated
- monitor joint range of motion ability
- position the joint in mild flexion
- provide heat or cold for local treatment to affected joint as prescribed
10
Q
Encourage high fluid intake of ______mL/day to prevent stone formation.
A
2000
