Gout

Question 1

What is it?

Answer 1

• Genetic disorder of purine metabolism, characterized by elevated serum uric acid

Question 2

What happens to the excessive uric acid

Answer 2

• changes into crystals and despots into peripheral joints and other tissues (kidneys)

Question 3

Where is gout most often seen

Answer 3

• knee
• great toe
• carpals

Question 4

Population

Answer 4

• M>F
• 30-40 yo

Question 5

Onset

Answer 5

• abrupt onset affecting single joint initially (typically 1st MTP)
• followed by remission 3-5 days but attacks become more frequent leading to severe joint destruction

Question 6

Medications

Answer 6

• NSAIDS, COX-2 inhibitors, colchicine, corticosteroids, ACTH, allopurinol, probenecid, sulfinpyrazone

Question 7

PT goals, outcomes, interventions

Answer 7

• education for injury prevention and reduction of involved joints
• education on dietary effects of the disease
• early identification of the condition with fast implementation of intervention

Question 8

what is seems on imaging

Answer 8

rat bite erosions