What are the preventatives
medications for headaches?
5
Abortive Medications for headaches?
6
1. MOA Inhibits the enzyme cyclooxygenase-2 (COX-2) 2. SE -Abdominal cramps -Nausea -Indigestion
Ibuprofen (Motrin)
Naproxen (Naproxen)
What are the barbiturates?
2
2. Fioricet
What is the Combination analgesics?
Midrin
1.Isometheptene/dichloralphenazone/acetaminophen
What are the Antiemetics?
4
Phenothiazines
Metoclopromide (Reglan)
Triptans are what category of drug?
Name the drugs in this class? 7
5-HT1 Receptor Agonists
Triptans
Sumatriptan (Imitrex)
administrations?
3
PO
SC
Nasal
How is Naratriptan (Amerge)
different from Sumatriptan (Imitrex)?
2
What makes Rizatriptan (Maxalt)
different?
Which triptan works well for menstrually related migraines?
All efforts should be made to initiate therapy as soon as possible after the first symptoms of the attack are noted, since success is proportional to rapidity of treatment. Why is this important?
lower dosages will be effective with less side-effects.
Ergot Alkaloids
Ergotamine tartrate (Ergostat, Ergomar) is associated with significant SE such as? 3
DHE Adverse effects more common adverse affects?
11
1. Burning or tingling sensation dry mouth 2. Dryness, soreness or pain in the nose 3. runny and or stuffy nose 4. change in sense of taste 5, Diarrhea 6. Dizziness 7. Fatigue 8. Headache 9. increased sweating 10. nausea and or vomiting 11. muscle stiffness
When would we use narcotics for heaches?
2
Meperidine (Demerol) Morphine Oxymorphone Hydromorphone (Dilaudid) Hydrocodone + acetaminophen (Norco) Oxycodone + acetaminophen (Percocet) Oxycodone Hydrocodone Fentanyl
What are some common combination therapies for headaches?
3