Which liver enzymes are raised in hepatitis
raised ALT
raised AST
raised GGT
General symptoms of hepatittis
- fever, arthralgia
- hepatomegaly
- abdominal pain
Which antibiotic may cause jaundice, and give an obstructive picture on LFTs
co-amoxiclav
Which Hep virus(es) only present acutely
Hep A
Which Hep virus(es) may present acutely or chronic
Hep B, C, D, E
Which virus is the commonest cause of acute hepatitis in UK
Hep E
Which group of people is most likely to develop chronic hepatitis after an acute infection
Children
Which hepatitis viruses have vaccines
Hep A
Hep B
Hep C
definition of chronic hepatitis
> 6 months
Treatment for Hep A
Supportive (fluids, manage temperature and jaundice, stop hepatotoxic drugs)
Treatment for Hep B, C, D, E
- interferons
- antivirals
What does this show:
- -ve: HBs-Ag
- +ve: anti-HBc, anti-HBs
Hep B immunity after infection
What does this show:
- -ve: HBs-Ag , anti-HBc
- +ve: anti-HBs
Hep B immunity after vaccination
What does this show:
- -ve: anti-HBs, anti-HBc (IgM)
- +ve: HBs-Ag , HBe-Ag, HBc-Ag, anti-HBc (IgG)
Chronic Hep B infection
What does this show:
- -ve: anti-HBs
- +ve: HBs-Ag , HBe-Ag, HBc-Ag, anti-HBc (IgM)
Acute Hep B infection
IgM and IgG - which is acute/ chronic?
IgM = acute IgG = chronic
Among the hepatitis viruses with potential to become chronic, which has highest risk of becoming chronic
Hep C
In which countries is Hep E highly endemic
Nigeria, India, China, Mexico
