Hypersensitivity classification

Question 1

type 1 (anaphylactic) mechanism and examples

Answer 1

IgE bound to mast cells binds with antigen
anaphylaxis
atopy

Question 2

type 2 (cell mediated) mechanism and examples

Answer 2

igm or igg binds with antigen on cell surface

autoimmune haemolytic anaemia
ITP
goodpastures
pernicious anaemia
acute haemolytic transfusion reaction

Question 3

type 3 (immune complex) mechnaism and example

Answer 3

free antigen and antibody (igg, iga) combine

SLE
post strep glomerulonephritis
extrinsic allergic alveolitis

Question 4

type 4 (delayed hypersensitivity) mechanism and examples

Answer 4

t-cell mediated

TB
graft versus host disease
contact dermatitis
extrinsic allergic alveolitis
MS
guillain barre