What is the priority concept for IBD?
Inflammation (electrolyte and fluid imbalance)
Where does water absorption occur?
Small intestine → large intestine
What conditions fall under IBD?
Crohn’s Disease and Ulcerative Colitis
Where can Crohn’s Disease occur?
Anywhere in the GI tract (mouth to anus)
What bowel layers are affected in Crohn’s?
All layers (transmural)
What is Crohn’s inflammation pattern?
Patchy inflammation throughout small and large bowel
Where does Ulcerative Colitis occur?
Large intestine only (rectum → colon)
What layers does UC affect?
Innermost layers (mucosa and submucosa)
What is UC’s inflammation pattern?
Continuous and uniform
Does IBD have periods of remission?
Yes, exacerbation and remission cycles
How is IBS different from IBD?
IBS = nerve issue, no inflammation
What causes IBD?
Genetics, immune response, environment, gut microbiome
How does the gut microbiome relate to IBD?
Changes affect immune function
Can IBD affect anyone?
Yes, and no cure
Important history cues for IBD?
Nutrition, elimination, travel, infections, NSAID use, arthritis
Physical symptoms during exacerbation?
Abdominal pain, rectal bleeding, urgency, mucous stools
Systemic symptoms?
Fatigue, weakness, anemia, dehydration, weight loss
Stool characteristics in IBD?
Loose, bloody, mucousy stools (20–30/day)
Which intestines does Crohn’s affect?
Small and large intestines
Which intestines does UC affect?
Large intestine only
Is Crohn’s inflammation continuous?
No, patchy
Is UC inflammation continuous?
Yes, spreads proximally
Common Crohn’s complications?
Fistulas, strictures, abscesses, obstruction
Which IBD has severe malabsorption?
Crohn’s Disease