IgG Structure
Monomeric
Hinge region present
Glycosylation is less, among all Igs
Most abundant Ig
IgG
Most versatile?
IgG
Can perform: phagocytosis, complement system, ADCC
Subclasses?
4 Sub Classes
IgG1
IgG2
IgG3
IgG4
Concentration wise order?
IgG1: 59%
IgG2
IgG3
IgG4: 3%
Molecular weight wise Order?
IgG3>IgG1=IgG2=IgG4
Opsonin order?
G1=G3>G4>G2
Act as a?
Opsoin
Complement Order?
G3>G1>G2>G4
major role in?
Chronic infection
Which Ig can cross the placenta?
IgG (except IgG2)