IgM Flashcards by KUMARI RHAEVA

Q

Structure?

A

pentameric
10 Ag binding site
60 CDR

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Q

Stability because of?

A

S-S bond
and J-chain

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Q

J chain in IgM

A

1 J chain
137 aa
15 KDa

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Q

J chain responsible for?

A

polymerisation

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Q

No. of Ag binds to IgM?
(If size is not mentioned)

A

5

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Q

No. of small Ag binds to IgM?

A

10

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Q

Concentration?

A

5-10% of total serum

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Q

oldest Ig?

A

IgM

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Q

Neopnate produce which Ig first?

A

IgM

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Q

formed during?

A

during primary response

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Q

Most effective complement activator

A

IgM
expose 3 Binding site @ CH2 domain

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Q

A

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