what is necessary to cause IE?
bactereamia in a pt with a predisposing cardiac lesion
what were pt’s given over last 50 years who were at risk of IE?
pre exposure prophylaxis - broad spec antibiotics
what has been proved recently against the use of pep?
no increase of fatalaties without pep not cost effective no link between IE and dental/non dental procedures reg TB = greater risk of IE no clinical effectiveness
what pt’s are at risk of IE?
valve replacement pt’s, valvular heart disease + stenosis/regurgitation, structural congenital heart disease, prev IE
what did the BDJ find in 2011?
antibiotic use decreased by 78.6% and no increase of deaths