Define codominance
Both alleles express themselves equally in the heterozygous condition, resulting in a phenotype that is intermediate between its pure-bred parents.
Dominant allele
Always expresses itself when present. It can express itself in the homozygous and heterozygous condition
Recessive allele
Only expresses itself in the homozygous condition. It is not expressed in the presence of a dominant allele
Discontinuous vs Continuous Variation
Albinism Gene Mutation
Sickle Cell Anaemia Gene Mutation
Cause:
- Recessive gene mutation
- Single base mutation, resulting in a different amino acid being coded for red blood cells.
Effect:
- Results in sickle shaped red blood cells
- Transport of oxygen is poor
- RBCs more fragile
- RBCs tend to agglutinate
Down Syndrome Chromosome Mutation
Cause:
- During fertilisation, either sperm or egg has 2 copies of chromosomes 21
- Results in 3 copies of chromosome 21 in the individual’s body cells.
Effect:
- Unable to reproduce
- Intellectual capacity reduced
Things that speed up mutation