What are the layers of the integument system?
Epidermis
Dermis
Hypodermis
What are the accessory structures of the skin?
- nail
Summarize the epidermis of the skin
Epidermis- epithelial tissue
5 layers
4 cells typed
Summarize the dermis
Dermis- connective tissue
2 regions
-nerve corpuscles
What is the hypodermis?
A subcutaneous layer
Describe the epidermis in detailed
5 layer
-stratified squamous keratinized epithelium
4 cell types:
-Kerwtinicytes, approx. 90%, produce protective protein keratin, water-repellant sealant
Melanocytes- 8% produce melanin determine skin color and absorbs uv light
-malignant melanoma
Give the layers of the epidermis from top to bottom
Describe the Corneum
25-30 layers flag dead cells- corneocytes/shames
Desquamation or shredding is continuous: 4-6 weeks
Keratin- protect underlying layers
Describe the luciderm
4-6 layers of dead cells
Contain large amounts of keratin
Describe the granulosum
3-5 layers of cells
Organelles begin to die- apoptosis
Keratohyalin protein assembles filaments into keratin
Lamellar granules-releases water repellent material between cells
Describe the spinosum
8-10 Layers of rounded cells
Keratinocytes contain coarser filament
Upper layer flatter in shape
Deepest layer highly active
“Spines” are appearent
Describe the basale
Actively dividing cuboidal- columnar cells
Stem cells produce new keratinocytes
Contain filaments which attach to desmosomes
Desmosomes anchor cells to each other.
Hemidesmosomes anchor cell to basement membrane
What is the papillary dermis?
What is Resticular Dermis?
What is the function of hair?
-protects from sunlight , frictions, heat loss, foreign particles
What is hair?
Extension of keratinized epithelium of Skin
Shaft- extends above the skin
Root- below the skin penetrating into the dermis
-Surrounded by hair follicle - two epithelial sheaths
Explain the structure of the root and shaft
Describe hair papilla
- located in the bulb
What are the functions of the stratum basale of the hair?
Gives rise to the hair matrix
What are nails?
Tightly packed keratinized epidermal cells
Explain the parts of the nail
Stratum corneum
-Body (plate) - hardened keratin
Stratum basale
- Matrix-deep to nail root, highly mitotic
Root-proximal part of the nail
Free edge
Describe sebaceous glands
Sebaceous gland- simple, branched acinar
Absent on soles and palms
Sac like base
Lumen filled with cells
Mostly empties at neck of hair follicle
Describe the sudoriferous sweat gland
Sudoriferous -sweat gland
Eccrine/Merocrine
-simple coiled tubular
Abundant on forehead, palms, soles
Excretory
Describe the apocrine sweat gland
Simple coiled tubular
Axilla, aerola
Adolescents