Interventional Pharmaceuticals

Question 1

What is the reversal agent for the vasodilator agents (dypridamole, adenosine, and regadenoson)?

Answer 1

Aminophylline

50-100 mg over 30-60 secs
repeat up to 250 mg

Question 2

Vasodilator that prevents reuptake of adenosine?

Answer 2

Diprydamole (persantine)

0.142 mg/kg/min over 4 mins

or 0.57 mg/kg injected at 3-5 mins

Question 3

Arteriolar vasodilator

Answer 3

Adenosine

0.140 mg/kg/min over 6 mins

or 0.84 mg/kg injected at 3 mins

Question 4

Beta 1 and beta 2 stimulator that increases muscle contractions

Answer 4

Dobutamine

5-10 ug/kg/min
increased every 3 mins up to 40 ug/kg/min
diluted in 50 mL of D5W or NS

Question 5

A2A adenosine receptor agonist vasodilator

Answer 5

Regadenoson (lexiscan)

0.04 mg in 5 mL saline

Question 6

ACE inhibitors

Answer 6

Captopril: 25-50 mg

Enalaprilat: 0.5-1 mg/kg or standard 40mg if pt takes a lot or habitually

Question 7

diuretic to evaluate renal obstruction

Answer 7

Furosemide (lasix)

0.04 mg/kg (max dose 2.5 mg)

Question 8

vasodilator for cerebral blood vessels

Answer 8

Acetazolamide (diamox)
1g (1000mg) and wait 15 mins until RPH administration

Question 9

contracts the GB

Answer 9

CCk (kinevac/sincalide)

0.02 ug/kg in 5mL sterile water given over 1 hour

Question 10

allows GB to fill, contracts sphincter of Oddi and increases pressure

Answer 10

Morphine

0.04 mg/kg or standard 2mg dose

Question 11

Antihistamine dosed at 300mg four times a day for 1-2 days

Answer 11

Cimetidine

Question 12

Antihistamine dosed at 20mg tablet

Answer 12

Famotidine

Question 13

Antihistamine dosed at 1 mg/kg IV over 20 mins

Answer 13

Ranitidine

Question 14

Anticoagulant that should not exceed 0.15 mL ____ per mL of blood (so to not impair diffusion of stannous ion)

Answer 14

ACD solution

Question 15

anticoagulant mostly used

Answer 15

Heparin

10-15 units / mL of blood

Question 16

blocks thyroid from taking up free or unbound radioactive iodine

Answer 16

Lugol’s solution (SSKI)

single 400mg dose of potassium iodide (KI)
OR
Lugol’s solution = to 100mg of elemental iodine (I2) at least 1 hour before RPH

Question 17

used for management of bradycardia, increases heart rate

Answer 17

Atropine

0.1mg/mL or 1mg/10mL syringe

Question 18

Renders pt hypothyroid to increase uptake of radioactive iodine

Answer 18

Thyrogen (recombinant human TSH or rTSH)

0.9mg
2 intramuscular injections on consecutive days in the buttocks

Question 19

mimics fatty meal, contracts GB, used instead of CCK

Answer 19

Boost/Ensure drink

8 oz