IPC Flashcards

(117 cards)

1
Q

Key pathogens requiring contact precautions?

A
  • MRSA
  • VRE
  • CPE
  • ESBL
  • MDROs
  • Acinetobacter baumannii
  • Clostridioides difficile
  • Norovirus
  • Scabies
  • Impetigo
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2
Q

Contact precautions Implementation measures?

A
  • Single room with en-suite
  • Dedicated patient equipment
  • PPE: (gloves and aprons)
  • Enhanced environmental cleaning
  • Chlorine‑releasing agent
  • Hand hygiene with soap and water (particularly for C. difficile and norovirus)
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3
Q

Key pathogens requiring droplet precautions?

A
  • Influenza
  • RSV
  • Bordetella pertussis
  • Group A Streptococcus
  • Neisseria meningitidis
  • COVID-19
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4
Q

Implementation measures of droplet precautions?

A

Implementation measures:

  • Single room
  • Surgical mask for healthcare workers if 2 meters of patient or when performing aerosol-generating procedures
  • Patient to wear fluid‑resistant mask during transfers
  • Eye protection if risk of splash
  • Appropriate respiratory hygiene/cough etiquette for patients
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5
Q

Key pathogens requiring airborne precautions?

A
  • TB
  • Measles
  • Varicella
  • COVID-19 (during aerosol-generating procedures)
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6
Q

Airborne precautions Implementation measures?

A
  • Negative pressure isolation room >6 ACH
  • FFP3 mask for HCW
  • Eye protection if risk of splashing
  • Door to room kept closed
  • Restriction of susceptible HCW
  • Respiratory protection for visitors
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7
Q

What is the HACCP?

A

Hazard Analysis and Critical Control Points
A systematic approach to the identification, evaluation, and control of food safety hazards.

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8
Q

What are the 7 HACCP principles?

A
  • Conduct a hazard analysis.
  • Determine the critical control points (CCPs)
  • Establish critical limits
  • Monitoring procedures
  • Corrective actions
  • Verification procedures
  • Establish record-keeping and documentation procedures
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9
Q
A
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10
Q

What IPC measures can consider to minimise risk of demolishing construction work in hospital buildings ?

A
  • Minimise dust by sealing the construction area completely
  • Move High risk pt away from the construction zone
  • FFP2 or above for high risk when transport through a construction area.
  • Positive pressure with HEPA room for high risk
  • Antifungal prophylaxis
  • Environmental sampling
  • Identify defects in ventilation
  • Determine efficacy of HEPA filters
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11
Q
A
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12
Q

Post op care to minimise post op surgical site infections?

A
  • Short hospital stay
  • Optimal wound care
  • Aseptic Non-Touch Technique (ANTT)
  • Remove drains early
  • Leave wound for ≥ 48 hours
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13
Q

Optimum timing for IV Abx peri-op for prophylaxis ?

A
  • For all Abx : 30–60 minutes before skin incision
  • Exceptions are vanc and levo (120 mins)
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14
Q

T/F:
Preoperative skin cleansing with chlorhexidine/alcohol-based preparations ?

A

T

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15
Q

What are the peri-op measures that proven to reduce rate of PJI rate ?

A
  • Chlorhexidine/alcohol-based skin preparations
  • Avoiding razors for hair removal
  • Staph aureus decolonization for high-risk procedures
  • Active warming > 36 °C
  • Perioperative glycaemic control
  • negative pressure wound therapy
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16
Q

Best way to pre-op shave hair to minimise SSI ?

A

Electric clippers with a disposable head on the day of surgery

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17
Q

Outbreak Charts and Epidemic Curves?

A
  1. Point Source Outbreak- single exposure event
  2. Continuous Common Source Outbreak- single source - extended period
  3. Propagated (Person-to-Person) Outbreak
    4-Intermittent Common Source Outbreak- intermittent exposure
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18
Q

VRE outbreak control measures?

A
  • Routine VRE screening for pt in high risk area on admission and weekly
  • Whole Genome Sequencing
  • to confirm hospital transmission
  • Environmental testing (VRE can be on bedside tables & infusion pumps)

  • Controle measures:
  • Patient Isolation and Cohorting
  • Enhanced Environmental Cleaning,
    deep decontamination with hydrogen peroxide vapour (HPV)/ Daily disinfection of medical devices
  • Staff Education eg Hand hygiene
  • Antimicrobial stewardship
  • Restrictions on visitors to high-risk areas
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19
Q

Surgical Site Infection Prevention Bundle

A
  • Appropriate hair removal (using clippers
  • Antibiotic prophylaxis
  • Maintenance of normothermia
  • Blood glucose control
  • Skin preparation with alcohol-based
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20
Q

VAP prevention bundle ?

A
  • Head of bed elevation to 30-45
  • Daily sedation interruption and assessment for extubation
  • PPI
  • DVT prophylaxis
  • Daily oral care with chlorhexidine
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21
Q

CAUTI prevention bundle ?

A
  • Assessment of indicatoion
  • Daily assessment for ongoing need
  • Immediate removal when ready
  • Aseptic insertion technique
  • Maintain Closed drainage system
  • Hand hygiene before and after manipulation
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22
Q

CDI controling bundle ?

A
  • Careful antibiotic prescribing
  • Hand hygiene with soap and water
  • PPE
  • Environmental cleaning with sporicidal
  • pt Isolation or cohort
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23
Q

Appropriate cleaning solution for C diff?

A

Disinfection with sporocidal solution:
- 1,000 parts per million (ppm) chlorine-based disinfectant solution
- soft furnishings: (pH neutral detergent and warm water or steam cleaner)
-

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24
Q

mrsa prevention bundle ?

A
  • Risk-based or universal screening
  • Isolation or cohort
  • Decolonisation therapy if appropriate
  • Enhanced environmental cleaning
  • Hand hygiene
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25
antimicrobial stewardship intervention bundle ?
- Daily review of prescriptions - Clear documentation of indication, dose, duration, and review date for all prescriptions - Adherence to local guidelines - Regular de-escalation - Stop Abx when appropriate
26
CPE spread prevention bundle?
- Risk assessment and screening of high-risk pt - Active surveillance in high-risk settings - Isolation/ cohorting if confirmed - Strict contact precautions - Enhanced environmental cleaning and decontamination
27
CVC/PVC Care bundle ?
- Hand hygiene before insertion and manipulation - Maximal sterile technique - Chlorhexidine - Optimal Site selection - Daily review for ongoing need
28
What is the standard isolation for CF patient during admission?
Single room with an en-suite
29
Recommended cleaning for IGAS infected pt room ?
- Clean with detergent and water - Followed by hypochlorite at 1000 ppm daily (or combined detergent hypochlorite product) - Communal facilities eg: baths and showers should be cleaned and decontaminated between all patients - s, linen and waste must be handled as hazardous
30
how to do erradicaton of GAS for a HCW contacts who have been screened and found to be positive for GAS ?
- Erradication therapy : penicillin V- amox or clinda x10 d - Clearance screens : take swabs 24 h after completing treatment, and again at 1, 3, 6, and 12 weeks
31
How to prevent A baumanii healthcare ass outbreaks?
1-Strict hand hygiene protocols 2-Contact precautions 3-Environmental cleaning and disinfection 4-Antibiotic stewardship to reduce selection pressure 5-Active surveillance in high-risk units
32
How to prevent toxoplasmosis in pregnancy ?
avoid undercooked meat, contaminated soil, and cat litter, and practice good hygiene
33
Disinfection?
Eliminates many or all pathogenic microorganisms, except bacterial spores
34
Low-level disinfection
- Can kill most vegetative bacteria, some fungi, and some viruses. - It is appropriate for non-critical items
35
Intermediate-level disinfection?
- Inactivates mycobacteria, vegetative bacteria, most viruses/ fungi - No effect in spores - Alcohols and chlorine compounds
36
High-level disinfection (HLD)?
- Inactivates all microorganisms except high numbers of bacterial spores. - Use Chemical germicides or pasteurisation 1- Hydrogen peroxide 7.5% 2- OPA 0.55% 3- Glutaraldehyde 2% - Required for semi-critical items like endoscopes.
37
The efficacy of disinfectants is influenced by?
Concentration Contact time pH Temperature Organic load Water hardness
38
Automated Disinfection Systems?
- Hydrogen peroxide vapour/aerosol systems - Ultraviolet (UV-C) light devices - Automated endoscope reprocessors (AERs)
39
Regulatory Framework and Standards for endoscope decontamination ?
- HTM 01-06, published by the Department of Health and Social Care - British Society of Gastroenterology (BSG) Guidelines 2020 - UK Medical Devices Regulations 2002 -
40
Endoscope Decontamination Process?
- Pre-clean or bedside cleaning - Trasfer to the endoscopy unit (<3h) - Leak test - Manual clean - Complete immersion in enzymatic detergent - Automated Endoscope Reprocessing AREs - drying and storage -
41
Which agent typically used in the automated endoscope reprocessing disinfection phase ?
- Peracetic acid - Chlorine dioxide
42
problems that can arise during Automated endoscope reprocessing?
- Occluded lumen or pump failure With failure of the alarm system - Wrong connection - Wrong program selected - Insufficient pump pressure - Incomplete cycle
43
Endoscopic drying methods following disinfection process?
- AER-integrated drying cycles - Flushing channels with filtered air or medical-grade alcohol, followed by air - Dedicated drying cabinets
44
endoscope storage types?
- Dedicated drying cabinets with HEPA-filtered air circulation (preferred) - Hanging in designated, clean, dry cabinets
45
What is the Maximum storage times for endoscopy before reprocessing?
- 72 hours in validated drying cabinets - 3 hours in conventional storage
46
How can we test if the endoscope is ready for use?
Check final rinse water
47
Endoscope final rinse water testing schedule ?
- Total viable count (TVC): Weekly testing - Environmental Mycobacteria: Quarterly - Pseudomonas aeruginosa: Quarterly - Endotoxin levels: if major water supply problems
48
High-Risk Endoscopes:
Bronchoscopes Cystoscopes Ureteroscopes Duodenoscopes used for ERCP
49
Low-Risk Endoscopes?
Gastroscopes Colonoscopes ENT scopes
50
50
what is the responsability of WSG?
Developing, implementing, and maintaining a Water Safety Plan (WSP) To ensure the safety of water systems
51
Members of WSG?
- Core members : 1- Microbiologest 2- IPC 3- Authorising engeneer (water) 4- Estate and property management - Non-core members : 1- Specialist Water Users (e.g renal unit , aquatic therapy ) 2-Housekeeping & Support Services 3- sterile service departments SSD 4- nursing 5-Augmented care
52
Prevention of HAP?
Dysphagia screening and management Oral hygiene protocols Early mobilisation Chest physiotherapy when indicated Hand hygiene compliance Enhanced cleaning of the hospital environment Isolation of patients with MDR pathogens Antibiotic stewardship programmes
53
VAP prevention bundle?
Head of bed elevation (30-45°) Endotracheal tubes with subglottic drainage Maintaining endotracheal cuff pressure at 20-30 cmH₂O Daily sedation interruption assessment for extubation Early mobilisation when possible Peptic ulcer prophylaxis Deep vein thrombosis prophylaxis Daily oral care with chlorhexidine
54
VAP risk factors?
1- Patient-Related Risk Factors - Advanced age - Male sex - Preexisting illnesses ( COPD, diabetes, heart failure, or kidney disease) - Immunosuppression - Low GCS - Burns - Smoking - Multiple-organ failure
55
VAP risk factors?
2- Treatment- related: - Prior antibiotic therapy . - Corticosteroid treatment - Prolonged duration of intubation and mechanical ventilation. - Reintubation - Cuffed endotracheal tubes - Lack of subglottic secretion drainage - Supine position
56
IPC measures in suspected pneumonic Plage case?
- FFP3 respirator- fit tested to the wearer - single-use fluid-repellent gown - single-use gloves - eye protection e.g. goggles or full face visor - linens should be bagged and managed as “infectious laundry” - hypochlorite solution (1000ppm available chlorine).
57
58
UN3373
"BIOLOGICAL SUBSTANCE, CATEGORY B"
59
In regards to infectious substance transport , what are the indicatives of Category A pathogens?
- UN2814 Infectious substance, affecting humans; or - UN2900 Infectious substance, affecting animals
60
What is the definition of category B substances ?
UN3373 Diagnostic specimens/ Clinical specimensdosnt meet the criteria of category A
61
Which staff memebers at higher risk of airborne hazards ?
- Surgical teams - Laboratory personnel - Pharmacy staff - Cleaning staff - Pathology
62
What is the filter grade and efficiency of UCV terminal?
- Filter Grade: EPA E10 - Efficiency: 85%
63
How do we measure the efficiency of the ventilation?
Answer - air change rate (Ach)
64
How do you monitor the AHU filters is efficient?
measure the pressure difference before and after the filter
65
What are the two types of theatres based on ventilation standards?
- Conventional - Laminar flow
66
What questions would you ask the maneufacturer when new theater is designed?
- The specification of the air-handling unit - What are the air change rates? - Airflow direction - Pressure - microbiological air sampling - for conventional theatre
67
UCV Validation checks?
- Sufficient air volume. - Air velocity under the canopy. - appropriate fitting of the HEPA filter - ensuring the airflow under the canopy can prevent any ingress of contamination.
68
What are the The key food safety legislation?
- The Food Safety Act 1990 - The Food Hygiene (England) Regulations 2006 - Regulation (EC) No. 852/2004 on the hygiene of foodstuffs - The Food Safety (Temperature Controls) Regulations 1995). EC 852/853 - HACCP (Hazard Analysis of Critical Control Points) 2004
69
What is the HACCP?
HACCP (Hazard Analysis of Critical Control Points) 2004
70
P620 PACKING INSTRUCTION (This instruction applies to UN Nos. 2814 and 2900)
- Leakproof primary pack - Leakproof secondary pack - If liquid contents , an absorbent material in sufficient quantity placed between the primary & secondary packaging - A rigid outer packaging - The smallest external dimension not less than 100 mm.
71
Packing instruction for UN 3373 Biological Substance Category B'.
packing instruction P650.
72
IPC Measures of PVL SSTI?
Contact precautions isolation in a single room, use of personal protective equipment (PPE) (most commonly plastic apron and gloves), meticulous hand
73
IPC meaurse for PVL and
- Same as SSTI Plus: - Wear PPE, including face and eye protection (e.g. surgical mask with integral eye protection) - if high risk exposure to confirmed case with no PPE , need screening b/w 3-7days post exposure
74
A HCW with a proven PVL-SA infection?
- should not work until the acute infection has resolved and 48 hours of a five day decolonization - assess for PVL-SA-related disease in close contacts and can be treated simultaneously - Follow up screens- three screens one week apart - should stop working if a further skin lesion develops.
75
PVL decolonisation ?
- Chlorhexidine 4% bodywash /shampoo or Triclosan 2% use once a day for 5 d - also as a shampoo on day 1,3,5 - Mupirocin (Bactroban Nasal) (use three times a day for 5 days
76
PEP in HIV positve donor with detectable VL?
- tenofovir disproxil 245mg OD - emtricitabine 200 mg OD - raltegravir 1200mg OD - Duration: 28 D
77
What are the exception in HIV PEP drugs ?
- Known resistance from index pt - Pregnant – reduce raltegravir dose to 400mg BD (from 1200mg OD) - Renal failure – can substitute TDF for TAF
78
What are the PEP Baseline testing for the index case ?
- 4th generation HIV test (HIV-1 Ag/Ab) - Hepatitis B surface antigen (HepBsAg) - Hepatitis C antibody (Hep C Ab)) Note : if high risk hep C (PWID) then a hepatitis C PCR (HCV PCR) or hepatitis C antigen (HCV Ag) can be done instead of Hep C Ab.
79
PrEP in pt with poor renal function?
Tenofovir alafenamide fumarate/Emtricitabine (FTC/TAF)
80
What is the standarsd PrEP treatment?
Emtricitabine and Tenofovir Disoproxil (FTC/TD)
81
List actions that can be taken if Legionella count from an outlet is more than 1000 CFU/L ?
- Resample the water system immediately - Conduct an immediate review of control measures - Risk assessment to identify necessary remedial actions - Consider disinfection of the entire water system - Arrange an alternative water supply
82
sensitivity
= TP / (TP + FN)
83
Specifity?
- TN/(TN+FP)
84
What are the principle of HACCP ?
1. Hazard analysis 2. Determine Critical Control Points (CCPs) 3. Establish critical limits 4. Monitoring procedures 5. Establish corrective actions 6. Verification procedures, and 7. Establish record-keeping and documentation procedures
85
What is the HACCP?
Hazard Analysis Critical Control Point
86
Bertussi high risk contact group 2?
ppl at increased risk of transmitting to ‘vulnerable’ individuals in ‘group 1’ if they have pertussis, who have not received a pertussis-containing vaccine more than one week and less than 5 years ago: A. Pregnant women who have reached 32 weeks’ gestation. B. HCWs who provide close personal care to infants (as defined in Group 1 above) and pregnant women. C. People whose work involves regular, close and prolonged contact with infants as defined in Group 1 D. People who share a household with an infant as defined in infants in Group 1
87
Antibiotics for Bertussis is only recommended to start with in the first 14 days from the onset of symptoms , Except ----?
Exception if household or other close contact who falls into priority Group 1 for public health action or is a pregnant woman, then can commene Abx within 21 days of onset of cough
88
Preferred Abx for Bertusis in pregnancy and neonate <1m?
pregnant erythromycin 500 mg po 6h for 7 days then Azithro then clary for neonate <1 month Clarythromycin BD for 7 days 7.5mg/kg
89
T/F: Contact of pertussis case need to be excluded from work and isolated
F Exclusion for contacts is not required just chemoprophylaxis for high risk group if exposure with in 14 days of symptoms
90
What is the recommended temperature of hospital water supply taps? [2 marks]
- The temperature should be at least 55°C within one minute of turning on the tap. - The temperature should be below 20°C within two minutes of turning on the tap
91
Name at least 3 engineering measures that can be used to prevent the growth of Legionella in the hospital water system ?
- Avoid TMT/TMV Maintain temperature at recommended range (above 55-60°C or below 20°C) - Regular flashing or unusual outlets - Avoid dead legs
92
Name 3 laws and guidelines underpinning the Legionella control in hospital water systems.
- The Health and Safety at Work etc. Act 1974 - The Control of Substances Hazardous to Health Regulations 2002 (COSHH) - Health Technical Memorandum (HTM) 04-01: Safe water in healthcare premises - The Health and Safety Executive's Approved Code of Practice L8 - The Control of Legionella Bacteria in Water Systems
93
List actions that can be taken if Legionella count from an outlet is more than 1000 CFU/L [4 marks]?
- Resample the water system immediately - Conduct an immediate review of control measures - Perform a risk assessment to identify necessary remedial actions - Consider disinfection of the entire water system - Arrange for an alternative water supply - Risk assessment and review of the patients
94
Avian flu IPC measures?
- Isolate the patient in a single occupancy room, preferably a respiratory isolation room and ideally under negative pressure - Minimise contact with staff - If a patient has to come out of the isolation room, should wear a surgical mask. - Full PPE: correctly fitted FFP3 respirator, gown, gloves and eye protection - Inform local lab and All samples must be handled at containment level 3 - Samples should be sent by Category B transport.
95
recommended PPE when working with poultry suspected of avian influenza?
Disposable coveralls or fluid-resistant gowns Gloves (disposable, preferably nitrile) Respiratory protection (N95 respirator or equivalent) Eye protection (goggles or face shield) Disposable boot covers or rubber boots that can be disinfected
96
What action has been taken in the UK to reduce the risk of VDPV2? ?
- Enhanced environmental and clinical surveillance - A targeted inactivated polio vaccine (IPV) booster campaign for children aged 1-9 years in affected areas. - Communication with healthcare professionals about the importance of polio vaccination.
97
What are the 3 types of VDPV2 - explain ?
- Circulating VDPV (cVDPV) - Immunodeficiency-associated VDPV (iVDPV) - Ambiguous VDPVs (aVDPVs)
98
Calculate ACH?
ACH= Air Supply Rate/ Room Volume
99
In UCV theatre, microbiological sampling is not done. How is annual verification done?
- Measuring Airflow Velocities, - Distribution - Confirming Air Change Rates. You can also mention: - Checking HEPA Filter Integrity. - Validating Pressure Differentials
100
Name one receptor for the rabies virus ?
Nicotinic Acetylcholine Receptor (nAChR)
101
HEPA filter?
high efficiency particulate air
102
list the steps of UCV System Commissioning?
- Satisfactory air velocity in the ultraclean zone - HEPA filter is effective and sealed correctly (leakage test - particle check) - Ultraclean air can prevent any ingress from outside (UVC Canopy entainment test)
103
Principle methods to avoid legionella in hospitals?
- Avoid stagnation of water (deadlegs ) - Avoid Under-use of taps - Ensure appropriate water tempreture (avoid 20-45) - Water treatment (e.g chlorination )
104
Regulatory Framework and Standards of EDU?
- HTM 01-06, published by the Department of Health and Social Care - British Society of Gastroenterology Guidelines 2020 - UK Medical Devices Regulations 2002 - Care Quality Commission (CQC)
105
How to acheive bacteria free water in EDU?
- Filtered water (0.2 μm filters) - Reverse osmosis (RO) water - Sterile water for specific applications
106
Steps of Endoscope Decontamination Process
- Bedside cleaningy - Trasfer to the endoscopy unit - Leak test - Manual clean (enzymatic detergent solution) - Automated Endoscope Reprocessing - ARE - Drying and storage
107
Automated Endoscope Reprocessing 5 phases ?
Detergent phase Rinse phase Disinfection phase ( peracetic acid or chlorine dioxide) Final rinse phase(s) Optional drying phase
108
what is used as disinfectant in AERs?
peracetic acid or chlorine dioxide
109
What are the common technical issues can occurs in AERs?
- Alarm failure in case of occluded lumen or pump failure - Wrong connection or wrong program selected. - Insufficient pump pressure - Incomplete cycle
110
Endoscopy final rinse water Testing Schedule?
- Total viable count (TVC): Weekly testing - Environmental Mycobacteria: Quarterly testing - Pseudomonas aeruginosa: Quarterly testing - Endotoxin levels: if major water supply problems identified
111
High-Risk Endoscopes?
Bronchoscopes Cystoscopes Ureteroscopes Duodenoscopes used for ERCP
112
Interpretation and Comment on Final rinse water with TVC 10-100cfu/100ml
- Unsatisfactory results - Do not reprocess until acceptable results obtained
113
Interpretation and action of final rinse TVC >100 cfu/100ml?
Unacceptable results Stop all reprocessing, recall and reprocess all unused endoscopes
114
What corrective action if PSA in the final rinse?
- Check the final filter between incoming water and the EWD chamber - EWD rinse self disinfection - Replace all non-metallic water contacts between the filter and the chamber - Use an extra filter between the final filter and the chamber (polishing filter).
115
Water Safety Group (WSG) responsabilty?
Is to creat , implement , and manitain a Water Safety Plan (WSP)
116
memebers of Water safety group?
Authorising Engineer (Water), Estates/Facilities Management, Infection Control, Medical Microbiology, nursing staff, and potentially other clinical or operational departments like Housekeeping or sterile services.