Ipratropium

Question 1

Indicators for use

Answer 1

Bronchospasm secondary to asthma or COPD

Bronchospasm secondary to airway burns, smoke inhalation or chest infection

Question 2

Contraindications

Answer 2

Severe allergy

Question 3

Cautions for use

Answer 3

NONE

Question 4

MOA ( mechanism of action )

Answer 4

Bronchodilator

Ipratropium is an anticholinergic agent with predominantly antimuscarinic activity. It antagonises (blocks) acetylcholine receptors, causing vagal inhibition resulting in bronchodilation.

Question 5

Dose and route

Answer 5

0.5mg ( 1 ampoule ) for children and adults
Given once with first dose of salbutamol

Nebulised 8L/m

Question 6

Side effects

Answer 6

Tachycardia
Dry mouth
Blurred vision

Question 7

Drug life span

Answer 7

Onset: 2-5 minutes
Duration: 6 hours