what are stem cells
the undifferentiated cells that are usually found in the bone marrow as well as the brain, heart, skin and other major organs.
have 2 functions
- make new stem cells
- to differentiate
examples of what stem cells may differentiate into
red blood cells
cardiac cells
enterocytes
fat cells
neuron
cell specialisation
occurs after differentiation where the cellular function stimulates - starts performing its needed function
two types of cell division
mitosis
meiosis - meiosis 1 and meiosis 2
mitosis
From one parent cell forms two new identical daughter cells where each contains exactly the number of chromosomes (diploid = 2n) and genetic material as the parent
mitosis stages
Interphase
Prophase
Metaphase
Anaphase
Telophase
Cytokinesis
purpose of mitosis
asexual reproduction
maintain genetic copy of the og cell
growth
repair during healing
meiosis
A type of cell division that only occurs in the reproductive cell (egg or sperm) that involves one parent forming 4 daughter cells (gametes) where each contains half the number of chromosomes (n = haploid) of the parent
stages of meiosis
Prophase 1
Metaphase 1
Anaphase 1
Telophase 1
Cytokinesis 1
Prophase 2
Metaphase 2
Anaphase 2
Telophase 2
Cytokinesis 2
purpose of meiosis
sexual reproduction
produce gametes
increase genetic variation
offsprings are unique from parents
what are daughter cells also classified as
haploid cells
2 in mitosis
4 in meiosis
how does meiosis increase genetic variation?
whats cell replication
the process where the genetic material is replicated during the process of cell division. Hence, cell replication correlates with cell division. This occurs right at the beginning of cell division when homologous chromosomes are produced
dna molecules in the body
1.deoxyribonucleic acid (DNA)
2. ribonucleic acid (RNA)
Both carry genetic materials that enable them to produce substances such as proteins.
DNA
a double-helix structure that resembles a twisted ladder, storing the genetic information. It’s made of two long chains of nucleotides, which are linked by a sugar-phosphate backbone on the outside and paired nitrogenous bases on the inside
Nitrogenous bases
Adenine (30%) - Thymine (30%)
Guanine (20%) - Cytosine (20%)
how does dna mutation occur?
when a cell replicates, the dna in the nucleus and cytoplasm has to be replicated exact but if not, mutation will occur and base pairs may be substituted, ultimately causing genetic disorders
what happens if theres an incorrect base pairing?
there is a ‘repair enzyme’ called DNA Polymerase I, that recognises the mismatched base pair, cuts out the the incorrect DNA sequence with minimal impact then replaces it with the correct base