Laxatives

Question 1

bulk-forming laxatives MOA

Answer 1

• increase water absorption
• softens and increases bulk of intestinal contents
• distention of colon increases peristalsis

Question 2

bulk-forming laxatives should not be used by individuals with…

Answer 2

abdominal pain, nausea, vomiting

Question 3

bulk-forming laxative drug names to know

hint: my neighbors sit and cell bulks of meth

Answer 3

methylcellulose (Citrucel)

Question 4

hyperosmotic laxatives MOA

Answer 4

creates gradient that draws fluid into colon to increase stool fluid content and stimulate peristalsis

Question 5

hyperosmotic laxatives AEs

Answer 5

abdominal bloating, rectal irritation, electrolyte imbalance

Question 6

hyperosmotic laxative drug names to know

hint: hyper Polly looked in the mirror

Answer 6

• polyethylene glycol 3350 (Miralax)

- lactulose

Question 7

saline laxative MOA

Answer 7

Similar to hyperosmotic - osmotic pressure pushes water/electrolytes into intestines

Question 8

saline laxative AEs

Answer 8

salts may cause issues with individual with diminished cardiac or renal function

Question 9

emollient laxative MOA

Answer 9

• facilitate water and fat absorption into stool
• lubricate fecal matter and intestinal wall
• known as fecal softeners and lubricant laxatives

Question 10

emollient laxative AEs

Answer 10

• usually well-tolerated

- skin rash, decreased vitamin absorption, electrolyte imbalance

Question 11

emollient laxative drug names to know

Answer 11

docusate (Colace)

Question 12

stimulant laxative MOA

Answer 12

stimulates peristalsis through enteric nervous system

Question 13

stimulant laxative AEs

Answer 13

Long-term use: dependence and damage to intestinal cells/loss of colon function

Question 14

stimulant laxative drug names to know

Answer 14

senna glycoside (Senna)