Lecture 9 Flashcards

(42 cards)

1
Q

What are the three stages when responding to “bend your arm”?

A

Think/decide → transmit decision → respond/contract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Which systems are involved in executing movement?

A

Brain, spinal cord, and muscles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the role of upper (pyramidal) motor neurons?

A

Transmit signals from the brain to lower motor neurons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the role of lower motor neurons?

A

Directly stimulate muscles to contract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the two main mechanisms of neuronal communication?

A

Action potentials and synaptic transmission

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is a stem cell?

A

A cell capable of self-renewal and differentiation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What determines stem cell potency?

A

Its ability to differentiate into different cell types

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the two main divisions of the nervous system?

A

Central nervous system (CNS) and peripheral nervous system (PNS)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which brain region is responsible for decision-making?

A

Frontal regions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which brain region processes sensory information?

A

Parietal regions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which brain region is responsible for vision?

A

Occipital lobe

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which brain region is responsible for hearing and memory?

A

Temporal lobe

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the main parts of a neuron?

A

Dendrites, cell body, axon, presynaptic terminal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Do neurons all have the same shape?

A

No, they vary widely in shape and size

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is neuronal determination?

A

The process by which a cell becomes a neuron

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What stage precedes nervous system development?

A

Blastulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What forms from the ectoderm during neurulation?

A

Neuroectoderm forming the neural plate

18
Q

What happens to the neural plate during neurulation?

A

It bends dorsally and forms the neural crest

19
Q

What forms when the neural plate closes?

A

The neural tube

20
Q

What happens to the notochord?

A

It degenerates into the nucleus pulposus

21
Q

What gives rise to the peripheral nervous system?

A

Neural crest cells

22
Q

What is the neural crest?

A

A transient embryonic stem cell structure

23
Q

What happens to neural crest cells?

A

They migrate and form diverse cell types

24
Q

What patterns the neural tube along the dorsal-ventral axis?

A

Morphogen (protein) gradients

25
How do morphogen gradients affect development?
They regulate transcription factor expression spatially
26
Which neuron types form ventrally in the neural tube?
Interneurons (V0–V3) and motor neurons
27
What are the stages of early brain development?
Three-vesicle stage and five-vesicle stage
28
What are neuroepithelial cells?
Neural stem cells that generate neurons and glia
29
What is interkinetic nuclear migration?
Movement of nuclei during the cell cycle in neuroepithelial cells
30
What is the result of symmetric division?
Two stem cells
31
What is the result of asymmetric division?
One radial glial cell and one neuron
32
What is the role of radial glial cells?
Act as stem cells and generate neurons and glia
33
What produces upper-layer cortical neurons?
Radial glial lineages and outer radial glial cells
34
What are basal progenitor cells?
Intermediate progenitors that amplify neuron production
35
What do outer radial glial cells (oRGs) do?
Generate many neurons in the superficial cortex
36
What happens when neurogenesis slows?
Radial glial cells switch to producing glia
37
What are astrocytes?
Star-shaped glia involved in BBB and neurotransmitter/K+ regulation
38
What are microglia?
Immune cells of the CNS derived from outside the CNS
39
What is the difference between oligodendrocytes and Schwann cells?
Oligodendrocytes myelinate multiple CNS axons; Schwann cells myelinate one PNS axon
40
What do ependymal cells do?
Line ventricles and regulate cerebrospinal fluid interface
41
What are satellite cells?
Support neurons in PNS ganglia and regulate microenvironment
42
What are the major cell types in nervous system development?
Neurons and glial cells