1
Q
Describe the method of LeDoux and colleagues 1988
A
Electrolytic lesions (which destroy neurons and fibers of passage) and ibotenic acid lesions (which spare fibers of passage) of CeA
2
Q
LeDoux et al 1988 Results
A
Lesion to caudal CG (by either method)- reduced conditioned freezing, no impact on arterial pressure
Lesion to lateral hypothalamus- impaired conditioning of changes in mean arterial pressure
CeA projection to Caudal Central Gray- conditioned emotional behavior (freezing)
CeA projection to lateral hypothalamus- conditioned autonomic response (mean arterial pressure)
