LES

Question 1

Criterios de clasificación LES por ACR (>4/11)

Answer 1

MD SOAP’N HAIR

• Malar rash
• Discoid rash
• Serositis (pleural, pericardial, peritoneal)
• Oral ulcer
• Arthritis
• Photosensitivity
• Neurologic abnormality (seizures, psychosis)
• Haematologic abnormality
• ANA (+)
• Immunologic abnormality
• Renal involvement

Question 2

Drogas que pueden causar Nefritis Intersticial

Answer 2

(mnemonic: Please Note All Drugs that Can Possibly Scar Renals):
• Penicillin derivatives
• NSAIDs
• Allopurinol
• Sulfa derived diuretics
• Cephalosporins
• Proton pump inhibitors
• Sulfa antibiotics
• Sulfasalazine
• Rifampin

Question 3

Drogas que inducen LES

Answer 3

Drug Induced Lupus: SHIPP - pedir anticuerpos anti histona (patrón homogéneo)
• Sulfonamides
• Hydralazine
• Isoniazid
• Procainamide
• Phenytoin

Question 4

Falsos positivos de VRDL

Answer 4

VDRL
Viral infection (EBV, hepatitis)
Drugs
Rheumatic fever
Lupus and Leprosy