exist as short, medium, and long chains of molecules
that are major constituents of triglycerides and
phospholipids
Fatty acids
simply linear chains of c-h bonds that terminate with a
carboxyl group (-COOH)
Fatty acids
can be extracted fr. cells only by organic solvents
LIPIDS
formed from one glycerol molecule with three fatty
acids molecules attached via ester bonds
Triglycerides
transported through the body by chylomicrons(exogenous) and VLDL (very-low-density
Triglycerides
metabolism of tiglyceride
unsaturated steroid alcohol containing four rings
Cholesterol
precursor for synthesis of bile acids, steroid/sex
hormones, and vit. D
Cholesterol
-LDL is the primary carrier
cholesterol
2 fatty acids + glycerol linked by ester bonds
Phospholipids
found on the surface of lipid layers, they are major
constituents of cell membranes and outer shells of llipoprotein molecules
Phospholipids
transport vehicles for lipids that contain varying
amounts of specific lipid, phospholipid and apoprotein
Lipoproteins
Chylomicrons
transport triglycerides after a meal
Chylomicrons
plasma-turbid/milky with creamy layer (chylomicrons
float on top) (frappe daw) (cotton)
Chylomicrons
apolipoprotein B-48 (Apo B48) (to make the lipids more
soluble to the blood for east transport)
Chylomicrons
carries endogenous triglyceride
VLDL
APO B100
VLDL, LDL
Intermediate-density lipoprotein (IDL)
elevated in type III hyperlipoproteinemia
(dysbetalipoproteinemia or broad beta disease)
Intermediate-density lipoprotein (IDL)
delays the clearance of IDL
Apo E
high risk of coronary heart disease
IDL
“bad cholesterol”
Low-density lipoprotein (LDL)
major cholesterol carrier
Low-density lipoprotein (LDL)