What is the function of the lymphatic system?
Return tissue fluid to circulation
Filter damaging material
Production of antibodies and lymphocyte maturation - defence for the body
Transport digested fat from intestine to liver/storage sites around the body
What are the components of the lymphatic system?
Capillaries, lymph vessels, ducts
Lymph nodes
Spleen
Thymus
Tonsils
Gut associated lymph tissue (GALT)
Lymph
What are the major lymphatic ducts?
Right lymphatic duct
Tracheal duct contribution
Thoracic duct
Cisterna chyli
What is the Right lymphatic duct?
Right caudal part of neck
Lymph from right thoracic limb and right side of neck and head
Right sup. Cervical, axillary and thoracic LN
Tracheal duct contribution - empties into right subclavian vein
What is the thoracic duct?
Main channel to return lymph of body into venous system
Caudally - start at sublombar region or diaphragmatic cruca
Cranially - left venous angle (subclavian vein and left internal jugular vein)
What is the cisterna chyli?
Two part lymph channel, retroperitoneally, association with cranial abdominal aorta
What are the major lymphatic nodes?
Parotid
Mandibular
Lat retropharyngeal
Superficial cervical
Axillary
Inguinal
Popliteal
Non palpable: femoral, mesenteric, bronchial
Where is the submandibular node?
2-5 nodes lying at edge of angle of the jaw
Where is the prescapula node?
Cranial to scapula
Where is the axillary node?
Within tissues of axilla (armpit)
Where is the popliteal node?
Within tissues of gastrocnemius muscle, caudal to stifle joint
Where is the inguinal node?
2 nodes either side of the groin, between thigh and abdominal wall
What is the anatomy of a lymphatic node?
Bean shaped - indented area named hilus
Capsule - fibrous connective outside layer
Cortex - location of residential lymphocytes
Medulla - contains tissue macrophages embedded in a coarse fibrous mesh
What is the spleen?
Largest lymphoid organ
Haemopoietic multi lobal
Attached to greater curvature of stomach on left side of abdomen
What is the function of the spleen?
Storage of blood, removal of old RBC, activation of WBC
Removal of bacteria and foreign material by action of phagocytic cells
Blood supply to the spleen?
Splenic artery (branch of celiac)
Splenic vein (portal vein)
Is the spleen essential?
Not essential to life
Can be surgically removed (splenectomy)
What is the thymus?
Thorax, cranial to heart
Prominent in young animals
What is the function of thymus?
Thymocytes
T cells
What are tonsils?
Lymphoid tissue in pharynx
Located at beginning of lymph drainage system, not along lymph vessels like lymph nodes
What is the function of tonsils?
Prevent spread of infection into respiratory/digestive systems
What is Gut associated Lymph Tissue?
GALT
Lymphoid tissue found in interstitial mucosa and submucosa
Largest lymphoid organ
What are peyers patches?
Located in wall of intestine
Assist with battle against invading antigens
How is lymph formed?
Arterial blood under pressure forces fluid out of capillaries and into tissues
Lack of blood pressure results in less fluid being absorbed back into veins = fluid accumulates in tissues (interstitial fluid)
Excess interstitial fluid drained to lymphatic capillaries
Lymphatic capillaries merge to form larger vessels With valves
Lymph is filtered in lymph nodes
Lymphatic vessels drain into ducts