Risk of fetal loss tends to increase/decrease over gestation?
decrease
Types of fetal loss and why its important
3
60% pregnancy gets lost in 1st trimester - human
still birth - low risk of occuring
fetal loss is important: signs are, if they can be rebreed, any future complications
why is abortion used instead of miscarriage terminology
induced or spontaneous
Describe the outcomes of fetal loss (all stages)
embryonic/early fetal loss -slightly longer cycle - sign
autolysed fetus - decomposed fetus
Briefly describe the rate of fetal loss across species
-rate across different types of fetal loss
Mummification vs maceration
what can we do? LA
retained in utero
Mummification = mummified fetus
Maceration = starts to breakdown and decompose fetus, bits of fetus seen
Induce parturition in mummification in cow - give PGF2a and/or oxytocin to help expel fetus.
polytoccus - wait for them to give birth to the mummified fetus
Maceration - v rare
caused by infectious organism
clinical symptomps smells and discharge
will need active treatment
If mare showing signs of estrous when she is meant to be in gestation what does this mean?
red flag! She probably aborted fetus
If a cow is not showing signs of parturition when she is meant to, what does this mean?
still birth - no signs of parturition
no change in size of placentomes in cow
what is needed for Mummification to occur
Ususualy in litter bearing species e.g pigs - can be one or some, all
define abortion storm
Higher than expected abortion rates in a group of animals
something maybe environmental that is causing this
What are some signs of infectious fetal loss how do you find the cause
-post-mortem of fetus and placenta
placentitis - well demarcated of colour change + cervical start
what are some common non-infectious causes of fetal loss
7
Curly calf - still birth
ectopic - within oviduct - life threatening
why investigate case of abortion?
-health of dam not long term issues
-look at aborted fetus and placenta
-characteristics of fetus, first time?
-gross lesions
-hormonal panel
-environmental issues - hot, toxic plants
-could diagnose pregnancy loss in litter bearing species e.g 6 vs 8 initial heart beats = check other offspring
what are some ways to prevent fetal loss
What are some indicators of pregnancy termination?
-approaches for inducing abortion
manual vs pharma techniques
spey for abortion
cause lutelolysis - PGF2a - dexamethasone
OR
induce parturition- combination of Oxytocin
shearing contractors - move from site to site - introduced pathogens -> campylobacter
High temperatures likely
handling/shearing - not that stressful
ryegrass = causes ataxia - obvious sign
How to induce abortion
rupture fetal membranes or removal protective barrier in cervix or remove progesterone bloc.
Progesterone block - target tinming of placental P4 takeover in certain species e.g C, E, M
Diagnose and monitor pregnancy
Diagnosis:
twins - fetal reduction e.g in mares
What are some signs of pregnancy diagnosis
overall and species specific
what to monito during maternal and fetal monitoring