malaria Flashcards

(10 cards)

1
Q

what is the cause ?

of malaria

A
  • p.Falciparum or P. Vivax
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2
Q

where is the disease an endemic ?

malaria

A
  • tropical and subtropical climates
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3
Q

what is meant by the term Antigenic type ?

malaria

A
  • they have different antigens on their surface that are very similar
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4
Q

what are the symptoms ?

malaria

A
  • mimics cold and flu
  • fever
  • anemia
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5
Q

what is the cycle inside the human ?

malaria

A
  • the p.Falciparum invades the liver cells and is hidden from the immune system
  • it then leaves the liver and can be detected
  • it enters the red blood cells which causes them to lyse
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6
Q

when should the disease be targeted in the life cycle ?

malaria

A
  • when there are sporozoite larvae in the blood plasma
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7
Q

Describe the transmission process

malaria

A
  • the female anopheles mosquito feeds on the human blood
  • if the person is infected, the mosquito will take up their infected blood
  • when the mosquito next feeds, they will pass on the infection into the persons blood.
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8
Q

how can you prevent the spread ?

malaria

A
  • interfere with the life cycle of the mosquito
  • use mosquito nets
  • insect repellent
  • wear long sleeves
  • reduce exposed skin
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9
Q

why have vaccines been difficult ?

malaria

A
  • it can have many antigenic types
  • they can also change the antigens on their surface and go through antigenic drift
  • antibodies can only attack the plasmodium outside of the cell
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10
Q

why are drugs less effective ?

malaria

A
  • parasite can only be attacked in the sporozoite stages nd can be avoided, which avoids an immune response.
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