Mantoux

Question 1

Pathophysiology of Mantoux

Answer 1

Test site t cell proliferation- release inflammatory markers- celks recruit- increased permeability - in duration

Question 2

Procedure of Mantoux

Answer 2

1 to 5 tu tween 80 intradermal on anterior side of arm
48-72 hrs
Horizontal induration is measured

Question 3

How do u interpret mantoux

Answer 3

5mm- negative 
5-9 mm - intermediate 
Consider positive in ic condition
Contacts
Xray lesion positive.
Esrd
10- closed groups- prisoners
Lab micro
Recent immigrants from high prevalence area
Infants, child <4

> 15- significant, infection, irrespective of bcg

Question 4

Uses of mantoux

Answer 4

Prevalence

Young children

Question 5

False positive

False negative

Answer 5

Prior bcg , tech , dose. Contaminated

Miliary , measles, hodgkins. Sarcoid , mal nutrition , immunosupression
Recent infection