Silico Tuberculosis Flashcards by Vijay Gandham

Pathogenesis

Macropgaes engulf- phagolysosome
Cm damage - other macrophage take up - same
Tnf alpha - fibrosis
Fibrosis interfere with clearance of mtb
Humaral and cell mediated immunity absent

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Radio

Nodule apical lobe doesn’t cross fissure
Silicotic nodule with cavitation
Sputum. Bronch,tblb

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Rx of silico tb

Ipt for 1yr
Limit exposure
Periodic cxr and tuberculin test

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Silico Tuberculosis Flashcards

(3 cards)