methylprednisolone

Question 1

name (trade)

Answer 1

solu-medrol

Question 2

class

Answer 2

corticosteroid

Question 3

description

Answer 3

synthetic steroid with potent anti-inflammatory properties

Question 4

mechanisms of action

Answer 4

inhibit substances that cause inflammation (cytokines, interleukin, interleukin, interferon) and inhibit the synthesis of pro-inflammatory enzymes

Question 5

onset

Answer 5

IV: varies
other: peak effects 4-8 days (IM)

Question 6

duration

Answer 6

1-5 weeks (IM)

Question 7

indications

Answer 7

severe anaphylaxis, asthma, COPD

Question 8

contraindications

Answer 8

none when used for severe anaphylaxis

Question 9

side effects

Answer 9

fluid retention, CHF< HTN, headache, nausea, malaise

Question 10

drug interactions

Answer 10

none in the prehospital setting

Question 11

supplied

Answer 11

multidose vial of 250 mg

Question 12

dose

Answer 12

IV/IM 125-250 mg