micro

Question 1

Name the 4 drugs that ater fungal cell membranes

Answer 1

-Amphotericin B (Polyene)
-Nystatin (Polyene)
-Azoles
-Terbina fine

Question 2

What is the function of Amphotericin B

Answer 2

Binds erosterols—> formes pores–> membrane leakage

Question 3

What is the function of Nystatin (polyene)

Answer 3

Same as Amphotericin B
- binds ergosterols–> formes pores—> membrane leakage

Question 4

What is the function of Azoles + what do they block ethylation of lanosterol

Answer 4

Inhibit ergosterols
- Block P-450-dependent dem

Question 5

What is the function of terbafine

Answer 5

Inhibits ergosteril synthesis