microscopy n bulk density

Question 1

why particle size is important?

Answer 1

flowability of powder
dissolution rate
bioavailability
stability
texture

Question 2

what is equivalent dia

Answer 2

diameter that is consider for irregular shape

Question 3

what are two types of microscope use to identify particles?

Answer 3

1. SEM-scanning electron microscopy

2. TEM-Transmission electron microscopy

Question 4

what is the usage of SEM

Answer 4

1. particle morphology

2. surface morphology of dosage form

Question 5

what is the usage of TEM

Answer 5

1. topography of particles
2. morphology,size and size distribution
3. crytsal property

Question 6

what are the methods used for particle size analysis

Answer 6

1. sieve analysis
2. coulter counter
3. laser scattering particle size

Question 7

what are the types of volume?

Answer 7

1. true volume
2. granular volume
3. bulk volume

Question 8

what is the importance of densities in tablet formulation?

Answer 8

flow property

compressibility

Question 9

classification of powder

Answer 9

coarse >355 micron
moderately fine >180-355 micron
fine >125-180 micron
very fine