what are the 3 phases of tissue response to injury and approx time
inflammatory response phase (4 days)
fibroblastic repair phase (4 days to 6 weeks)
maturation-remodeling phase (couple weeks to 2-3 yrs)
What are the 5 signs of inflammation (SHARP)
Swelling
Heat
altered function
redness
pain
What are the 4 goals of the inflammatory response phase
protect
localize
decrease injurious agents
prepare for healing and repair
What are the 3 Key stages of Phase 1 Inflammatory Response Phase
Vasoconstriction: occurs upon tissue disruption to seal blood vessels
Vasodilation: occurs within minutes after initial vasoconstriction (increase blood flow and leads to swelling)
Clot formation: important to avoid disruption
How long does vasodilation and clot formation last in phase 1 inflammatory response phase
vasodilation: 24-36 hours
clot formation: 12-28hours post injury
What was the old steps for first 28 hours post injury in acute management (RICE)
Rest, Ice, Compression: keeps fluid in vessels, elevation: reduces pressure in vessel and allows for fluid to drain
What is the new acronym for first 48 hours in acute management (POLICE)
Protection
Optimal Loading
Ice
Compression
Elevation
How to ice in acute management (kinds of ice to use) 4 things
frozen water, crushed ice/smaller cubes better
cold water immersion
reusuable gel and instant cold
What are the optimal time frames of ice application and location of the ice
20 min on 1 hour off
multiple applications if possible
apply directly to skin, unless there is allergy
What are 4 sensation explanations of icing you can explain for the first time
1st: Cold/pain
2nd: Burning
3rd: Aching-throbbing
4th: Numbness
What are 5 contraindications to ice
Reynaud’s syndrome: ice allergy change colors in cold anf stuff
Diabetes
Recent surgery
Sensitive skin
Altered sensation
What is the use for ice practically and how should it be prioritized compared to protection and optimal loading
Ice is best for short term relief, prioritize protection and optimal loading
What does fibroblastic repair phase also referred to as and main process
fibroplasia: pain and tenderness subsides during this period as healing occurs
formation of delicate connective tissue; consists of substances that develop collagen or scar tissue
What happens in the fibroblastic repair phase phase 2 (2 things + barrier to recovery)
tensile strength increases with proliferation collagen
normal sequence= minimal scarring
prolonged scar tissue formation can create barriers to injury recovery
- pain
-adhesion of non effective scar tissue
What are 3 things to know Phase 3, Maturation and Remodeling
Long term process
realignment of collagen is relative to applied tensile forces
continued breakdown and synthesis of collagen, more strength
tissue gradually assumes normal appearances
How does Chronic inflammation impede healing
3 things to know
Result of failed acute inflammation response
subacute inflammation represents prolonged inflammatory response phase
may be caused by further disruption to injured tissue in early fibroplastic phase
What are the 4 types of soft tissue + other tissue
Epithelial tissue
Connective tissue: tendons and ligaments
Muscle tissue
nerve tissue
bone
How do ligaments healing
follow conventional healing sequence through acute repair and remodeling phases
What happens in the repair phase for ligaments (and the kind of stability its integral for)
laying down of collagen, matures and realign in reaction to stresses
integral in regaining static stability of a joint
In ligaments, with intraarticular tears ______ will dilute hematoma and ________ clotting
synovial fluid; prevent clotting
delays healing
Why must muscles be strengthened to reinforce the joint
dynamic stability makes up for the reduction of static stability provided by the ligament
What happens after there is bleeding in skeletal muscle (2 things)
bleeding is followed by proliferation of fibroblasts
- bruising
collagen will mature and orient along lines of tensile force
What is the main way skeletal muscles heal, and the time frame
Myoblastic cells from=regeneration of new myofibrils
Healing could last 6-8 weeks depending on injury and severity (primary vs accessory)
What are the two general things to know about tendon healing
requires dense fibrous union of injured tissue in order to regain function
Abundance of collagen is required for good tensile strength