Module 1 - Nucleic Acids Flashcards

(25 cards)

1
Q

nucleic acid monomer are called:

A

nucleotides

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2
Q

what are the functions of nucleic acids?

A

storage and transmission of genetic material; guiding gene expression

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3
Q

what are the three main components of a nucleotide?

A

nitrogenous base, pentose sugar, phosphate group

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4
Q

what is the role of the nitrogenous base in a nucleotide?

A

carrying genetic code

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5
Q

what is the role of the phosphate group in a nucleotide?

A

connects nucleotides in a chain

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6
Q

what are the two nitrogenous base families?

A

pyrimidines and purines

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7
Q

pyrimidines

A

cytosine, thymine and uracil

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8
Q

purines

A

adenine and guanine

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9
Q

what is the complementary strand of the following strand: 5’ TCAGGACTTA3’

A

3’AGTCCTGAAT5’

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10
Q

nucleic acids are formed via ____

A

polymerization of nucleotides

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11
Q

define a phosphodiester bond

A

covalent bonds between the 5’ phosphate of one nucleotide and the 3’ hydroxyl of the next

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12
Q

describe a sugar phosphate backbone

A

the repeating structural framework of nucleic acids

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13
Q

the primary structure of nucleic acids includes:

A

a single-stranded sequence of bases

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14
Q

the secondary structure of nucleic acids includes:

A

the double helix with two strands running antiparallel

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15
Q

what type of bonds hold together nitrogenous bases?

A

hydrogen

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16
Q

adenine pairs with…

17
Q

guanine pairs with…

18
Q

the sugar phosphate backbone faces the ____ in the double helix

19
Q

the nitrogenous bases face the ____ in the double helix

20
Q

describe the tertiary structure of nucleic acids

A

DNA can supercoil around histones

21
Q

describe the process of DNA replication

A

parent strands break by separating hydrogen bonds - free nucleotides pair with each - new strands are built via phosphodiester linkages - two identical daughter molecules are formed

22
Q

nucleotide sequences are always written from the ____

A

5’ end to the 3’ end

23
Q

If a DNA double helix contains 28% T nucleotides, what is the percentage of A nucleotides?

24
Q

if a DNA double helix is 100 nucleotide pairs long and contains 25 adenine bases, how many guanine bases does it contain?

25
how do the structures of RNA and DNA differ?
adenine pairs with thymine in DNA and uracil in RNA