Module 3 - Part 1

Question 1

Gregor mendel

Answer 1

• established many rules of hereditary
• hereditary factors determine traits (ie. genes)
• different forms of “hereditary factors” come together during fertilization & sep. during gametogenesis

Question 2

Mendel’s First Law

Answer 2

The law of segregation:
- diploid organism genes has two alleles - one from each parent
- probability of haploid gamete receiving one allele of a gene = similar probability to flipping a coin

Question 3

Pedigree analysis

Answer 3

the study of an inherited trait in a group of related individuals to determine the pattern & characteristics of the trait

Question 4

Autosomal recessive inheritance

Answer 4

• heterozygote shows no symptoms: recessive
• the disease/mutant trait only appears when a person carries both mutant alleles

Question 5

Cystic fibrosis

Answer 5

a rare inherited disorder resulting in respiratory & digestive problems
- over accumulation of sticky mucus
- results from mutations in the CFTR gene
- autosomal recessive
- probability = 0.25

Question 6

Autosomal dominant inheritance

Answer 6

inheritance of one allele is sufficient to cause the trait or disease = dominant allele
- eg. huntingtons disease