Mo-99 is produced by the fission of ___
U-235
The product is often referred to as
fission moly
Physical half-life of Mo-99
66 hr/2.8 days
Physical half-life of Tc-99m
6hr
Composition of ion exchange
(Al2,O3)
Physical half-life of Tc-99m
6hr
99mTc has a gamma ray energy of ___ that is ideal for imaging and a half-life of ___ that is convenient.
140 keV
6 hours
Pertechnetate (99mTcO4) is produced directly from 99Mo using a ___
saline eluant
99Mo decays to 99mTc, and ___ is added to the generator when 99mTc is needed.
saline
Saline passes through the column to elute (wash off) the 99mTc in the form of __
sodium pertechnetate
99Tc decays by isomeric transition where ___ of nuclear transformations result in emission of a 140-keV gamma ray.
88%
Saline passes through the column to elute (wash off) the 99mTc in the form of __
sodium pertechnetate
The half-life of 9ºMo is 66 hours, which allows the generator to remain useful for approximately ___
1 week (~2.5 half-lives).
A 99mTc generator is normally eluted ___ over the course of a week and then replaced.
daily
The process of removing Tc-99m from the Mo- 99/Tc-99m generator is known as ___.
elution
Before use in patients, or for making Tc-99m-labeled radio-pharmaceuticals, the eluate must undergo ___
quality control testing
The maximum buildup of Tc99m activity occurs at how many hours after elution
23 hours
A Mo99 generator thus takes approximately how many hours to reach equilibrium
24 hours
The eluate (Tc-99m) is extracted in the form of ___ solution
Sodium Pertechnetate
In equilibrium, a 1 Ci 99Mo generator also has approximately ___mCi of 99Tcm
1000
-Most commonly used in regional radiopharmacies, come with a reservoir of normal saline (0.9%).
• Wet systems
Common in imaging clinics, a volume-calibrated saline charge is placed on the entry port and a vacuum vial is placed or the collection port.
Dry system
In equilibrium, the activity of 99mTc is ~___ of the 99Mo activity.
90%
___is the name given when the parent radionuclide is short lived.
Transient equilibrium
