1
Q
What is the only commercially available monobactam
A
Aztreonam
2
Q
which micro organisms is aztreonam active against
A
Only aerobic gram -ve rods
pseudomonas aeruginosa
Enterobacteriaceae
treat serious systemic infections caused by gram -ve path (pneumonia,meningitis, sepsis)
(Not ACTIVE AGAINST GRAM +VE)
3
Q
Route of adm
A
IV OR IM
4
Q
Excretion
A
renally(can accumulate in people with renal failure)
5
Q
adrs
A
Aztreonam is relatively nontoxic, but it may cause phlebitis, skin
rash and, occasionally, abnormal liver function tests
6
Q
why is it used for pts who are allergic to penicillin
A
This drug has a
low immunogenic potential, and it shows little cross-reactivity with antibodies
induced by other β-lactams.
Antibiotics
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