What are the most common types of cancer in men in the US?
prostate, colorectal, melanoma, urinary, lung
How many cancer deaths are related to obesity/overweight, physical inactivity and poor nutrition?
1/3
What nutrients support DNA repair?
folate, selenium, allyl sulfer compounds
supplementation of this nutrient is suspected to increase rates of colorectal cancer?
folate
Once carcinogenesis is intiated, what provides substrates for DNA synthesis and accelerates cancer cell proliferation
folate
protective hormone that decreases insulin resistance and inflammation and promotes apoptosis
adiponectin
_____ supplements probably protect against colorectal cancer, but levels above ____ mg/day increase risk for prostate cancer
calcium; 1500 mg/day
increasing foods high in selenium and lycopene are productive against what cancers?
prostate
What are allium vegetables and what type of cancer do the protect against?
garlic, onions, leeks; stomacl cancer
Healthy patterns of diet and PA can prevent what percentage of the most common cancers
33%
What has been shown to protect against colorectal cancer?
garlic and foods that contain dietary fiber
What are the 2 validated screening tool for outpatient setting?
PG-SGA and MST
Tumor control rate is reduced by ___% eith every day that radiation therapy is interrupted?
1%
What % of patients with advanced cancer will develop sarcopenia?
50%
ECOG score of ___ would indicate a patient is only capable of limited self-care, confined to bed or chair>50% or waking hours
3
ECOG ranges
0- normal/fully functional; 3- 50%; 5 dead
Karnofsky scores
80-100 normal; functional; 50-70 unable to work; 40-0 severe decline- dead
Adults of nutrition support need how much CHO and fat per ASPEN guidlines?
CHO <7g/kg/day and fat </= 2.5g/kg/day
micronutrients lost during inflammatory process due to sequestration in liver and reticuloendothelial system, increased urinary losses, and protein catabolism
selenium, copper, iron, zinc
% of patients that are normometabolic at diagnosis
44%
what two adipokines are influenced by adiposity that may modulate carcinogenesis?
leptin and adiponectin
what is a key regulator of energy balance and appetite control?
leptin
what adipokine does not increase as body fat increases?
adiponectin
malnutriton is reported in approximately how many cancer patients at this time of diagnosis? and up to what percent over the course of care?
15-20% at diagnosis; 80% over care course