What connective tissue surrounds individual muscle fibers?
Endomysium
What are multiple muscle fibers bundled together called?
Fascicles
What connective tissue surrounds each fascicle?
Perimysium
What connective tissue surrounds the entire muscle (all fascicles)?
Epimysium
What structure binds several muscles into functional groups?
Deep fascia
What is the purpose of connective tissue layers in muscles?
They provide structure, protection, and transmit force from muscle to tendon.
What are the dark bands in skeletal muscle called?
A bands
What are the light bands in skeletal muscle called?
I bands
What is found in the center of the A band and contains only thick filaments?
H band
What structure is located in the middle of the H band?
M line
What structure marks the boundaries of a sarcomere?
Z disc (or Z line)
Where is the Z disc located?
In the center of the I band
What protein provides elasticity and stabilizes thick filaments?
Titin
What is the functional unit of muscle contraction?
The sarcomere (from one Z disc to the next)
What are the two forms of actin?
G-actin (globular) and F-actin (filamentous)
What does G-actin form when polymerized?
F-actin, the helical filament of the thin filament
What protein covers actin’s active sites in a relaxed muscle?
Tropomyosin
What protein complex binds calcium and moves tropomyosin?
Troponin
What is the long tail portion of the myosin molecule called?
The rod region
What part of myosin forms cross-bridges with actin?
The globular heads
What enzyme activity is found in the myosin heads?
ATPase activity (for energy during contraction)
What happens when calcium binds to troponin?
Tropomyosin shifts, exposing actin’s binding sites for myosin attachment.
What is the mechanism of muscle contraction called?
The sliding filament mechanism