1
Q
MoA of mycophenolate mofetil
A
inhibits purine synthesis
2
Q
s/e of mycophenolate mofetil
A
- bone marrow supression
- pure red cell aplasia
- hypogammaglobulinaemia
- bronchiestasis
3
Q
s/e of mycophenolate mofetil
symptoms to report if bone marrow supression
A
- infections
- bruising
- bleeding
4
Q
s/e of mycophenolate mofetil
what to do if pt develops pure red aplasia
A
reduce dose or discontinue
5
Q
s/e of mycophenolate mofetil
what levels need to be measured if pt develops hyopagammaglobulinaemia
A
measure immunoglobulin lvls in recurrent infection
6
Q
s/e of mycophenolate mofetil
symptoms of bronchiectasis
A
consider if persistent cough or SoB develop
7
Q
MHRA warning of mycophenolate mofetil
A
tetrogenic
8
Q
MHRA warning
contraception advise with mycophenolate mofetil
A
- women = 1 effective contraception during tx and 6wk after (2 methods ideal)
- men = effective contraception during and 90DY after tx (+partners)
