Ondansetron
Primary emergency indications
All undifferentiated nausea and vomiting
Ondansetron
Contraindications
Concurrent
apomorphine use
Ondansetron
Precautions
a) Liver disease - must not exceed 8mg/per day,
b) Long QT syndrome,
c) Pregnancy.
Ondansetron
Key timings
Oral (ODT) wafers
Onset = 2min
Peak = 20min
Duration = 2hrs
Ondansetron
Presentations
a) Wafer/Tablet containing 4mg or 8mg
b) 8mg in 4mL glass ampoule
Paracetamol
Presentation
500mg tablet or capsule
Paracetamol
Primary emergency indications
Mild pain including headache
Paracetamol
Contraindications
Age = < 1 month
Already administered in past 4hrs
Total intake in past 24hrs exceeds 4g (adult)
Paracetamol
Precautions
a) Hepatic impairment
b) Renal impairment
c) Elderly/frail
d) Malnourished
Paracetamol
Key timings
Onset = 30min
Peak = NA
Duration = 4hrs
Paracetamol
Pharmacology/
Actions
Provides analgesic and antipyretic effects.
Salbutamol
Primary emergency indications
a) Asthma
b) Anaphylaxis
c) COPD
d) Other causes of bronchospasm
Salbutamol
Contraindications
Nil of significance in the above indications
Salbutamol
Key timings
Onset = 5-15min
Peak = n/a
Duration = 15-50min
Salbutamol
Special notes/ Important interactions
Continue to administer oxygen 8L/min between doses
Salbutamol
Pharmacology/
Actions
Stimulates Beta2 adrenoreceptors = relaxation of bronchial smooth muscle (aka bronchodilation)
Methoxyflurane
Primary emergency indications
For pain relief of moderate - severe pain.
Pt must be able to self administer
Methoxyflurane
Contraindications
a) Head injury or loss of consciousness,
b) Exceeding total dose of 6mL in 24hr period,
c) Renal impairment/failure,
d) Malignant hyperthermia - personal or family history.
Methoxyflurane
Precautions
a) Continuously assess Pt LOC,
b) Concurrent use with Oxytocin may cause hypotension,
c) Pre-eclampsia
Methoxyflurane
Key timings
Analgesic effects starts after 8-10 breaths.
Lasts for approx
3-5min once discontinued.