Describe size, myelination, and targets of A-alpha fibers
largest, myelinated, large motor neurons
Most important signals will be sent through what type of neuron
large, myelinated fibers
List the nerve fibers that Dr Schmidt told us to focus on in descending size/speed
A-alpa
A-beta
A-gamma
A-delta
C-unmyelinated
What fibers send dull, achy, slow pain
C fibers
what fibers send fast pain signals
A-delta fibers
What are muscle spindles/spindle receptors and what nerve fibers are involved
-sensors built into the muscle fibers that feedback to the spinal cord and brain to tell us information about the muscle we are trying to move - stretch sensors - PROPRIOCEPTION
-A - beta fibers
You’re injecting blocking agents into the neck - which nerve fibers do you want to be sure are blocked and why?
A-alpha fibers because they are the hardest to block requiring more anesthetic. If you block the ones requiring higher doses, then you can be sure that all the rest are blocked too.
What happens when GABA is activated by ethanol?
the nervous system stops releasing its own GABA, leading to the symptoms of alcohol withdrawal (agitation, anxiety, potentially DTs, seizures etc)
What is the receiving end of a neuron
dentrites
what is the primary function of the axon hillock
the decision-making zone of the axon. It will receive all the excitatory and inhibitory signals coming in from the dendrites and will decide if an action potential will fire or not.
Describe the axon hillock anatomically
the specialized region of the neuron where the axon originates from the soma (cell body)
What are the 2 general cell types of the nervous system
neurons : predominant, message sending around body
glial cells: supporting cells, help us to move action potentials around the body, clean things up, etc
Cell nucleus
cell body/neuron
Sending end of the neuron
axon
Myelin’s function
increases speed and efficiency of a message being sent
Sending neuron
pre-synaptic, sending end
Post-synaptic neuron
receiving neuron, target
Where proteins are made in a neuron
cell body
How do proteins get sent down long neurons
train-track system?
What are astrocytes
supporting cells that wrap around neurons, maintaining them and cleaning up degenerations
What is the resting membrane potential of a typical decision-making neuron and why
Vrm is around -60, primed for firing with minimal stimulation
What keeps the breaks on our nervous system
GABA mediated chloride permeability
Where typically can you find the highest concentration of the inhibitory synapses?
Why?
the axon hillock. We need strategically placed inhibitory synapses to prevent over firing of the neurons since they are easy to excite
What type of neuron has a cell body in middle, myelination of both projections
What senses are they associated with?
Special senses: olfactory, retina