What kind of signal does the striatum send out?
What neurotransmitter?
Inhibitory
GABA
What does the STN do in the Indirect pathway?
Produces more glutamate to activate the Globus pallidus internus
What is the outcome if the globus pallidus internus is activated?
It produces GABA to inhibit the thalamus! This inhibits voluntary movement!
What happens between the striatum and the thalamus in the direct pathway?
Striatum inhibits GPI
The GPI can then not inhibit the thalamus
Voluntary movement occurs because the thalamus is active!