Class
Vasopressor
Supplied
4 mg / 4 ml (1 mg/ml) 4 ml vial
Adult dose
2-12 mcg/min IV, titrate to a MAP or BP.
Max adult dose
12 mcg/min
Pediatric dose
0.1 mcg/kg/min IV, titrate to goal MAP or BP, usual dose is 0.05 to 0.3 mcg/kg/min.
Max pediatric dose
6 mcg/min
Action
Alpha and beta adrenergic activity with potent inotropic effect and coronary artery vasodilation.
Considerations
Inject 4 mg /4 ml vials (16 ml) into 250 ml of NS. (64 mcg/ml). Risk of extravasation, use large peripheral veins or central line if available.
Side effects
CNS: Headache
CV: Tachycardia, hypertension, dysrhythmias
Indication
Hypotension, Shock