Propofol

Question 1

Brand name

Answer 1

Diprivan, Propoven

Question 2

Class

Answer 2

Intravenous sedative-hypnotic agent for use in the induction and maintenance of anesthesia or sedation.

Question 3

Adult Dose

Answer 3

Loading dose: 0.5-5 mg/kg

Maintenance infusion: 2-10 mg/kg/hr

Question 4

Pediatric dose

Answer 4

N/A

Question 5

Action

Answer 5

Thought to produce its sedative/anesthetic effects by the positive modulation of the inhibitory function of the neurotransmitter GABAa through the liand-gated GABA receptors.

Question 6

Indication

Answer 6

IV sedative-hypnotic agent

Question 7

Contraindication

Answer 7

Hypersensitivity

Question 8

Side Effects

Answer 8

Bradycardia, Hypotension, Hypertension, Decreased cardiac output.