What initiates inspiration?
Contraction of the diaphragm and external intercostal muscles
What happens to the thoracic cavity during inspiration?
expands
How does thoracic expansion affect pleural pressure?
Pleural pressure becomes more negative (pressure in thoracic cavity drops)
What happens to transmural pressure during inspiration?
increases
transmural pressure?
alveolar pressure − pleural pressure
How does increased transmural pressure affect the lungs?
expand
What happens to intrapulmonary airways during inspiration?
expand due to increased transmural pressure
What happens to alveolar volume during inspiration?
Alveolar volume increases
How does increased alveolar volume affect alveolar pressure?
Alveolar pressure decreases
When does air flow into the lungs during inspiration?
When alveolar pressure falls below atmospheric pressure
Which structures are affected by pleural pressure?
Intrapulmonary structures only
Which pressure acts on extrathoracic airways?
Atmospheric pressure
What happens to extrathoracic airways during inspiration?
constrict
Why do extrathoracic airways narrow during inspiration?
Atmospheric pressure exceeds airway pressure → inward collapse tendency
what happens to pleural pressure in expiration?
increase
what happens to alveolar pressure in expiration?
increase
What causes alveolar pressure to rise during expiration?
Elastic recoil of the lungs as pleural pressure increases and lung volume decreases.
normal inspiratory-to-expiratory time ratio at rest?
1 : 1.5–2
Why does peak inspiratory flow occur late in inspiration?
Intrapulmonary airways progressively expand
Airway resistance decreases as lung volume increases
Flow rises and peaks near end-inspiration
Why are inspiratory sounds loudest at end-inspiration?
airflow is highest when airway resistance is lowest near peak lung volume
Why does peak expiratory flow occur early in expiration?
Lung elastic recoil is strongest at high lung volumes
Pressure gradient is greatest at the start of expiration
Flow then gradually declines as recoil decreases
end-expiratory pause?
A brief period at the end of expiration when:
Alveolar pressure = atmospheric pressure
No net airflow
What primarily drives airflow during expiration?
Elastic recoil of the lungs
normal bronchovesicular sounds?
Low-pitched, continuous lung sounds heard during normal pulmonary auscultation