3 types
normal
transient
oppurtunistic
normal flora
adapted to body and always present
on body surface- never under epithelium
commensal and mutualistic
commensual
provide no benefit but do not harm
mutualistic
provide benefit to human
benefits to humans
produce bacteriocidal (toxic) substances alter pH to ferment lactose to acid outcompete opportunists for resources (microbial antagonism) inactivate bacterial toxins produce b12 and Vitamin K
1st colonizers
from birth canal- Lactobacillus, Staph, Strep
large intestine- Bifidobacterium
skin
Staph and Micrococcus
mouth, nose and upper throat
Strep and Lactobacillus
intestines
E. coli, Klebsiella, Enterobacter, Lactobacillus
vagina
Lactobacillus and Candida
urethra
Strep and Staph
transient flora
removable with washing and disinfection
usually not harmful
Opportunistic
disease causing
sometimes normal flora that gets under epithelium