Ondansetron: Introduction
Anti-nauseant and anti-emetic
Selective 5-3HT receptor antagonist blocking serotonin centrally in the chemoreceptor trigger zone and peripherally on the vagus nerve terminals
Ondansetron: Indication
Moderate to severe nausea
Active vomiting
Prophylaxis for eye and spinal injuries
Ondansetron: Contraindications
Paediatrics <2 years old
Hypersensitivity
Ondansetron: Considerations
Hangover: MH DD R
Malaise/fatigue
Headache
Drowsiness
Dizziness
Rash/allergic reaction