Otic Dosage Forms

Question 1

Types of otic dosage forms

Answer 1

• solutions
• suspensions
• ointments

Question 2

Pharmacological classes

Answer 2

• antibiotics
• analgesics
• anti-inflammatory
• cerumen (earwax) removing (cerumen - secretions of the sweat and sebaceous glands. removed by mineral oil, vegetable oil/surfactants)

Question 3

Anti-infective preparations of otic dosage forms

Answer 3

• formulated into eardrops (solutions/suspensions) in a vehicle of anhydrous glycerin/propylene glycol which their hygroscopic nature helps to kill microorganisms
• often combined with analgesic or local anesthetic
  e. g. chloramphenicol, colistin sulfate, neomycin

Question 4

Anti-inflammatory preparations of otic dosage forms

Answer 4

• useful against inflammation and swellings

e. g. hydrocortisone, dexamethason

Question 5

Analgesic preparations of otic dosage forms

Answer 5

• useful solutions containing analgesic/local anesthetic in a vehicle of propylene glycol/anhydrous glycerin -> hygroscopic vehicle reduces swelling of tissues as it absorbs moisture
  e. g. auralgan otic solution