what is pathology
the study of diseases
what is a disease
any abnormal disturbance pf the function or structure of the body as result of some type of injury
what is pathogenesis
occurs after injury, the events leading up to or producing the cellular damage that lead to observable changes known as manifestations
what are manifestations
observable changes as result from disease and damage
the display or disclosure of characteristic signs and symptoms of an illness
what is a sign? what is a symptom
these are the ways disease is characterized
signs- measurable. BP or body temp
symptoms- how patient feels. hot or sick
what are the 2 ways disease is described?
acute disease and chronic disease
what is acute disease
quick on set and last short amt of time
what is chronic disease
manifests slowly and last a long time. these diseases can also have acute episodes
what is a diagnosis
the name of the disease the patient is believed to have
what is a prognosis
the predicted course and outcome of a disease
what are the 6 disease classifications
1- inflammation & infectious disease
2- neoplastic disease
3- congenital and hereditary disease
4- metabolic disease
5- degenerative disease
6- traumatic disease
what is inflammation? what are the steps?
results from the bodys reaction to a localized injurious agent.
-blood flow increases to that area and vascular permeability
-WBC respond and go to the injured area
-phagocytosis of necrotic tissue
-repair of tissue, granulation tissue (scar tissue)
what are the 4 types of injury
infective
traumatic
toxic
allergic
explain the 5 signs of acute inflammation
1- heat/ calor- caused by increased blood flow
2- redness/ rubor- increased capillary permeability
3- swelling or edema/ tumor- caused by the shift of protein & fluid into interstitial space
4- pain/ dolor- results from increased pressure of fluid on nerves
5- loss of function- if cells lack nutrients or swelling interferes w action
what irritations can cause chronic inflammation
smoking
bacterial infection
long term imm responses
what is infection
an inflammatory process caused by a disease causing organism. the invading pathogen multiplies and causes injury effects
what are some types of infection
bacterial
viral
parasitic
fungal
can infection occur without inflammation? can inflammation occur without infection ?
no
yes
what factors promote healing
youth
good nutrition
adequate hemoglobin
good circulation
clean wounds
minimal complications
what factors delay healing
old age
poor nutrition
anemia (low blood iron)
poor circulation
infection
morbidity or underlaying disease
steroid use and chemotherapy
what complications can arise from healing
loss of function
contractures or obstructions (shrinking scar tissue)
adhesions (2 scar tiss fuse together)
hypertrophic scar tiss (overgrow)
what are neoplasms? what are the 2 types
new abnormal tissue growth that is no longer controlled. these cells do not respond to normal cellular start and stop messages of mitosis.
benign neoplasm
malignant neoplasm
what is a benign and malignant neoplasm?
b- remain localized and noninvasive
m- cancer, continue to grow and spread to invade other tissues
what is congenital disease
diseases that are present at birth resulting from genetic or environmental factors. can be hereditary but could occur from maternal infection, radiation, or drugs