Paget’s disease of the bone complications:
High output cardiac failure and Osteosarcoma
Codman triangle
Osteosarcoma
Soap bubble (reactive bone elements)
Giant cell tumor
Epiphyseal long bone tumor
Giant cell tumor
t (11,22)
Ewing sarcoma, fusion protein EWS-FLI1
Small blue cell tumor, anaplastic
Ewing Sarcoma
remember, the derivation from neuroectoderm