clinical use of calcium channel blockers
hypertension
angina
atrial fibrillation
atrial flutter
adverse effects of calcium channel blockers
- cardiac depression
- AV block
(non-DHP)
clinical use of nitrates
- angina
- acute coronary syndrome
- pulm edema
antianginal therapy
nitrates
beta blockers
decrease O2 demand
digoxin MOA
inhibits Na/K ATPase –> Na/Ca inhibited indirectly –> increased intracellular Ca –> positive ionotropy –> stimulates vagal nerve –> decreased HR
clinical use of digoxin
- HF (increases contractility)
- A Fib
adverse effects of digoxin
- hyperkalemia
- cholinergic: nausea/vomiting, diarrhea, blurry vision, arrhythmias, AV block
names of class IA drugs
Quinidine, Procainamide, Disopyramide
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clinical use of class IA aa drugs
- atrial & ventricular arrhythmias
- SVT
- V Tach
adverse effects of class IA aa drugs
- torsade de point
- SLE
- Cinchonism
names of class IB aa drugs
IIB: LIDocaine, MEXilTine
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clinical use of class IB aa drugs
- acute ventricular arrhythmias
- Best post MI
names of class IC aa drugs
iC: Flecainide, Propafenone
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clinical use of class IC aa drugs
- SVT
- A Fib
clinical use of class II aa drugs
- SVT
- A Fib (ventricular rate control)
- A Flutter (ventricular rate control)
clinical use of class III aa drugs
- A Fib
- A Flutter
- V Tach
clinical use of class IV aa drugs
- SVT
- A Fib (rate control)
names of class III aa drugs
AIDS
Amiodarone, Ibutilide, Dofetilide, Sotalol
clinical use of adenosine
diagnosing/terminating SVT
decreases AV node conduction
clinical use of Mg2+
- torsade de point
- digoxin toxicity
